Consider eating a complete meal of carbs, protein, and fat within 2 to 3 hours of exercising, or a smaller meal focusing on carbs and protein 1 to 1.5 hours.
You can take it with or without food. If it upsets your stomach, take it with food. Take your medication at regular intervals. Do not take it more often than.
Generally speaking, it's a good idea to have a little bite before lacing up. “It's better to eat than not eat before a run, even if you're not hungry,” says.